Summary
Zopiclone (Fig.1) – branded as Zimovane – is a hyposedative, non-benzodiaepine cyclo-pyrrolone [1], which is also an agonist at the type A -aminobutyric acid (GABAA) [2], meaning that zopiclone is known to produce activity at the GABAA receptor complex (Fig.1) [3; 4]. In addition, the duration of zopiclone’s effects and action is determined by its pharmacokinetic profile, which suggests a delayed elimination time when compared to the hypnotic agent Zaleplon [3]. Importantly, zopiclone is a commonly prescribed hypnotic drug which is usually employed – short-term – to treat sleeping difficulties [5]. Zopiclone is considered a ‘Z-drug’, having notable high-affinity binding to the GABA receptor [6]. Comparatively, zolpidem and zaleplon bind to the -1 subunit of the GABA receptors [7].
sospaintingnc –
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Glenn Coombs (verified owner) –
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truth (verified owner) –
Excellent product at a reasonable price. My sleep quality has improved significantly.
david-6997 (verified owner) –
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Katrina Burge –
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jshuler (verified owner) –
The product is great quality – I can confirm it is genuine. My rating has nothing to do with ModaPharma they did an excellent job.
The medication, however is another thing. Go search for “lunesta bad taste.” (This is a precursor to Lunesta so essentially same side effects)
Within minutes of swallowing the pill I got a horrible bitter metallic sort of just gross taste in my mouth and it wasn’t just a taste it was also a smell every time I would breathe in or out I could smell it. It’s not a matter of the pill dissolving in your mouth it’s when the pill hits your bloodstream. 2 days later and my sense of taste still has not returned to baseline. Ice water tastes bitter and gross. Gatorade is just finally starting to not taste gross. Diet Coke was disgusting yesterday today it’s almost tolerable. I will never take this medication ever again.